clinical_trials
Effects of semaglutide on cardiac structure and function in heart failure with preserved ejection fraction and obesity: a pre-specified cardiac magnetic resonance substudy of the CAMEO-SEMA trial
Confidence95·multiple reportsImportance97NP-EVT-20261108-771044D
Nature Medicine, Published online: 08 November 2026; doi:10.1038/s41591-026-04787-8 As presented at the 2026 AHA Scientific Sessions, a cardiac magnetic resonance substudy of the CAMEO-SEMA trial showed that semaglutide significantly improved cardiac structure and function, including left atrial reservoir strain and left ventricular filling dynamics, in individuals with heart failure with preserved ejection fraction and obesity.
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Effects of semaglutide on cardiac structure and function in heart failure with preserved ejection fraction and obesity: a pre-specified cardiac magnetic resonance substudy of the CAMEO-SEMA trial
Barry A. Borlaug · 11/8/2026, 12:00:00 AM
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