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clinical_trials

Opposing microbiome-mediated axes link modifiable lifestyles to health and chronic diseases

Confidence95·multiple reportsImportance97NP-EVT-20261105-3FD83BE

Nature Medicine, Published online: 05 November 2026; doi:10.1038/s41591-026-04744-5 Fecal shotgun metagenomics from 6,803 adults in the Japanese 4D cohort and microbiome-based prediction scores validated across 13 independent and geographically diverse cohorts revealed two opposing microbiome-mediated axes linking lifestyle to health and 15 diseases.

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Opposing microbiome-mediated axes link modifiable lifestyles to health and chronic diseases
Naomi Uemura · 11/5/2026, 12:00:00 AM
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