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Venousization enables angiogenesis in the absence of VEGFR signalling

Confidence95·multiple reportsImportance97NP-EVT-20261104-120E94D

Nature, Published online: 04 November 2026; doi:10.1038/s41586-026-11224-w Longitudinal tracking of endothelial cells shows they can adapt to loss of VEGFR2 and form new functional vessels, challenging conventional views of the essential role of VEGF receptors in angiogenesis and providing insight into resistance to anti-VEGF therapies.

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Venousization enables angiogenesis in the absence of VEGFR signalling
Rui Benedito · 11/4/2026, 12:00:00 AM
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