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clinical_trials

[Articles] Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials

Confidence96·multiple reportsImportance98NP-EVT-20261029-BA1D318

Across the available randomised trials, short-term adverse event rates were low with both pathways, but the pooled safety estimate remained imprecise. On average, earlier cardiac troponin retesting did not reduce emergency department length of stay or clearly increase direct discharge, and substantial between-study heterogeneity indicates that treatment effects might not translate uniformly across health-care systems. For hospitals considering transitioning from a 0/3 h to a 0/1 h pathway, imple

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[Articles] Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials
Jasper Boeddinghaus, Michael Kunz, Pedro Lopez-Ayala, Aleem Khand, Kenji Inoue, James Hatherley, Joseph Miller, Kristina Lambrakis, Joshua Emakhu, Bernard Cook, Paul Collinson, Cynthia Papendick, Sazzli Kasim, Farina Mohd Salleh, Andrea Wiencierz, Paolo Bima, Luca Crisanti, Luca Koechlin, Michael Christ, Òscar Miró, Fulvio Morello, Peiman Nazerian, Mohammed Abubakr, Dominik Roth, Felix Mahfoud, Richard Riley, James McCord, Derek P Chew, Christian Mueller, Global 0/1 h Consortium · 10/29/2026, 11:30:01 PM
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