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Alzheimer’s disease genetics converges on microglial and neuronal dysregulation

Confidence95·multiple reportsImportance97NP-EVT-20261028-C9B7C0F

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11206-y A multi-ancestry study of Alzheimer’s disease identifies new risk loci and potential drug targets, implicates microglia and neurons, and reveals a larger common-variant contribution than previously estimated.

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Alzheimer’s disease genetics converges on microglial and neuronal dysregulation
Alexander W. Charney · 10/28/2026, 12:00:00 AM
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