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clinical_trials

Tandem repeat variation shapes immune cell type-specific gene expression

Confidence95·multiple reportsImportance97NP-EVT-20261028-5EF201A

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-10438-2 Whole-genome sequencing and cell-level gene expression measurements show that length variation in tandem repeats in the human genome contributes to cell type-specific differences in gene regulation and expression, as well as the architecture of complex traits.

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Tandem repeat variation shapes immune cell type-specific gene expression
Daniel G. MacArthur · 10/28/2026, 12:00:00 AM
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