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Presynaptic homeostasis mediated by exocytosis of a SNARE protein

Confidence95·multiple reportsImportance97NP-EVT-20261028-18B3A1E

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11201-3 Experiments show that when subjected to high-frequency stimulation, excitatory neurons exhibit a presynaptic form of homeostatic plasticity mediated by the exocytosis of v-SNARE protein VAMP7 and the resulting inhibition of P/Q-type calcium channels.

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Presynaptic homeostasis mediated by exocytosis of a SNARE protein
Robert H. Edwards · 10/28/2026, 12:00:00 AM
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