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Programmable design of functional proteins from natural language

Confidence95·multiple reportsImportance97NP-EVT-20261021-FB85411

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11205-z Pinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation product yields without iterative optimization.

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Programmable design of functional proteins from natural language
Fajie Yuan · 10/21/2026, 12:00:00 AM
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