clinical_trials
WEE1 opposes APC/C CDH1 activity to promote S phase entry
Confidence95·multiple reportsImportance97NP-EVT-20261021-2A33048
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11188-x Experimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the toxic side effects of WEE1 inhibitors in cancer therapies.
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WEE1 opposes APC/C CDH1 activity to promote S phase entry
Alexis R. Barr · 10/21/2026, 12:00:00 AM
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